Because cold & flu viruses are often spread by hand contact, Kleenex brand has developed a tissue for your whole business. Each anti-viral tissue has three soft layers, including a moisture-activated middle layer that kills 99.9 percent of cold & flu viruses in the tissue within 15 minutes. It's virucidal against Rhinoviruses Type 1A & 2, Influenza A & B, & Respiratory Syncytial Virus. Each box comes with germ-fighting tissues, & each tissue features small blue dots on the interior layer to signal that they're antiviral. So whether you are a teacher caring for children, a commercial operator with a big staff or a business owner who cares about your employees' health, these antiviral facial tissues can be an important part of keeping your crew healthy, year-round.