When you're tired of taking & retaking pills every few hours to deal with long-lasting aches & pains, Aleve can help. Just one tablet is strong enough to provide pain relief that can last up to 12 hours, which means no more stopping throughout the day to take more tablets. Aleve is an over-the-counter (OTC), nonsteroidal anti-inflammatory drug (NSAID) that provides temporary relief from minor aches & pains. It also temporarily reduces fever. Contains: Naproxen Sodium; Description: Aleve 220 mg Tablets.